Week 3 NFL betting guide, props, lines: Model, expert, parlay, DFS and best season-long fantasy picks revealed

A pair of 2024 playoff teams have started off at 0-2, with the Texans and Chiefs both hoping to find the win column on Sunday. Houston is a 1.5-point road underdog to Jacksonville, per the Week 3 NFL odds, while Kansas City is favored by 5.5 points at the Giants on Sunday night. Both squads are also winless against the spread, which may influence Week 3 NFL betting for their games. Meanwhile, despite the teams’ struggles, individual players like Patrick Mahomes, Travis Kelce and C.J. Stroud may still find their way into many Week 3 NFL prop bets.

Will the Chiefs or Texans find success either on the scoreboard or versus the line? Another 0-2 team in the Bears is actually favored versus the 1-1 Cowboys. Being winless is certainly a motivating factor to play your best, and factors like this should be considered before making Week 3 NFL predictions.

If you are looking for NFL picks, NFL parlays, Fantasy football rankings or NFL DFS picks for Week 3, SportsLine has you covered with its proven model, Machine Learning Model and team of experts.

NFL parlay picks could generate massive payouts

SportsLine’s model has returned well over $7,000 on top-rated NFL betting picks since its inception, so those picks can confidently be used to fill out NFL parlay picks on betting apps. The model has built a five-team parlay for Week 3 that pays 25-1, and one of the legs is the Philadelphia Eagles (-3.5, 44.5) covering against the Los Angeles Rams. The model has Philly covering in well over 60% of simulations, and the rest of the five-team parlay can be found here.

You can also bet this parlay at DraftKings, where you can get $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket. 

Fantasy rankings to help you win your matchups

SportsLine’s model simulates every game 10,000 times, which has helped it produce better Fantasy rankings than human experts over the last few seasons. It has revealed its Week 3 Fantasy football rankings that can be used to make start-sit decisions. Chicago’s Rome Odunze is projected to be a top-10 wide receiver this week, and it also has full rankings for every position right here. 

NFL DFS picks from top experts 

SportsLine has a DFS Optimizer that simulates every game 10,000 times and uses info from the SportsLine Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on sites like FanDuel and DraftKings. It has Minnesota’s Carson Wentz as its top value pick at quarterback, while Washington’s Zach Ertz is one of the best value picks at tight end for Sunday’s main slate. Here are its complete Week 3 NFL DFS rankings. 

Senior Fantasy Writer Heath Cummings has locked in his projections for every Fantasy relevant quarterback, running back, wide receiver and tight end in your leagues. Not only do you get statistical projections as well as Fantasy point totals for every player in different scoring formats, but Cummings also includes DFS prices and values to help build winning DFS lineups each week. Get his Week 3 Fantasy and DFS projections right here. You can also make NFL prop bets on Wentz, Ertz and others with the Underdog Fantasy promo code CBSSPORTS2. 

Pick at Underdog Fantasy and get $50 in bonus funds after making a $5 wager:

Advanced NFL model simulates every game 10,000 times 

SportsLine’s model enters Week 3 of the 2025 NFL season up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 37-17 run on top-rated picks dating back to 2024 and has revealed picks for every Week 3 NFL game. One of its favorite picks is the Packers (-8.5) covering at Cleveland, which cashes over 60% of the time. You can find the model’s picks for every game here. 

You can also use the latest FanDuel promo code to get $300 in bonus bets instantly:

NFL Vegas expert picks revealed 

SportsLine has an expansive team of NFL experts who provide quality betting advice for every game on the schedule. Analyst Sia Nejad, who is on a 4-0 roll (+400) with ATS picks in Falcons games, has revealed his best bets for Week 3. He is backing Atlanta (-4.5) to cover on the road versus the Panthers. Nejad’s NFL best bets for Week 3 can be found here.

Eric Cohen, who went 12-4 with his Week 1 NFL picks and then 11-5 in Week 2, has exact score predictions for all 16 games. He is high on the Bears (-1.5, 50) to defeat the Cowboys, 31-27, on Sunday. Hit any of his exact score picks and you’re looking at a payout well over 100-1. That pick, along with his prediction for every game, is available here.

Bills vs. Dolphins Thursday Night Football picks

The Week 3 NFL schedule starts with the 2-0 Bills hosting the 0-2 Dolphins on Thursday. Buffalo is 13-1 versus Miami over their last 14 meetings, and Bills coach Sean McDermott is 9-0 versus Miami at home. SportsLine’s model likes the Bills (-11.5) to cover the largest Week 3 NFL spread, with Buffalo winning ATS in almost 60% of simulations in an A-rated pick. NFL expert Mike Tierney, who is 26-14-3 (+1072) on his last 43 side picks in Bills games, has analyzed Dolphins vs. Bills and locked in his TNF best bets right here.

Use the BetMGM bonus code CBSSPORTS and get up to $1,500 in bonus bets if your first bet loses:

Chiefs vs. Giants Sunday Night Football picks

The only Week 3 matchup of 0-2 teams takes place on Sunday night as the Giants host the Chiefs. New York is 7-0 all-time at home versus the Chiefs, making the Giants the only NFL team to be undefeated at home versus Kansas City. SportsLine’s model likes the Chiefs (-5.5) to cover, projecting they win versus the spread in almost 60% of simulations. NFL expert R.J. White, who is 46-22 (+2105) over his last 68 picks in Giants games, has analyzed this matchup from every angle and locked in his best bets for SNF right here.

Ravens vs. Lions Monday Night Football picks

A potential Super Bowl preview takes place on Monday night with the Lions visiting the Ravens (-5.5). These teams combined for 93 points in Week 2 victories, with nine passing touchdowns and zero turnovers. SportsLine’s model likes the Over (51.5) in this game, predicting 54 combined points. It has also revealed its picks on the spread and money line. The advanced model has also made stat projections for Lamar Jackson, Jared Goff and others, and it calls for one of the quarterbacks to pass for nearly 250 yards and 2.17 touchdowns on average. See who it is right here.