Heat vs. 76ers odds, line, spread: 2022 NBA picks, March 21 predictions from proven computer model

The Philadelphia 76ers will take on the Miami Heat at 7:30 p.m. ET on Monday at the Wells Fargo Center. Philadelphia is 43-27 overall and 20-16 at home, while Miami is 47-24 overall and 21-15 on the road. The Heat are sitting atop the Eastern Conference standings; Philadelphia is 3.5 games back in third place. 

Miami is favored by 2.5-points in the latest 76ers vs. Heat odds from Caesars Sportsbook, while the over-under is set at 215.5. Before entering any Heat vs. 76ers picks, you’ll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 21 of the 2021-22 NBA season on a stunning 78-48 roll on all top-rated NBA picks, returning over $2,400. Anyone following it has seen huge returns.

Now, the model has set its sights on 76ers vs. Heat. You can head to SportsLine to see its picks. Here are several NBA betting lines for 76ers vs. Heat:

• 76ers vs. Heat spread: 76ers +2.5
• 76ers vs. Heat over-under: 215.5 points

What you need to know about the 76ers

Philadelphia will be wrapping up a three-game homestand on Monday night. The 76ers opened with a 111-101 win over Dallas on Friday night before losing to Toronto by five points on Sunday. They led by 16 points in the early stages, but the Raptors battled back to take the lead down the stretch. 

Center Joel Embiid leads Philadelphia with 29.8 points, 11.3 rebounds and 4.3 assists per game. Newly acquired point guard James Harden is averaging 22.3 points, 11.2 assists and 7.3 rebounds, while Tobias Harris is adding 17.6 points and 6.9 rebounds. The 76ers have won 10 of their last 13 home games against Miami. 

What you need to know about the Heat

Miami continues to hold its multi-game advantage over Milwaukee, Philadelphia and Boston at the top of the Eastern Conference standings. The Heat have won three of their last four games, including a 120-108 win over Oklahoma City on Friday night. They just wrapped up a seven-game homestand that began with a 99-82 win against Philadelphia on March 5. 

The Heat were without Jimmy Butler (ankle), Victor Oladipo (back) and Gabe Vincent (toe) in the win over Oklahoma City. Butler, who is the team’s leading scorer, is listed as questionable for Monday’s game, while Oladipo and Vincent will both remain sidelined. Miami has covered the spread in its last eight road games. 

How to make 76ers vs. Heat picks

The model has simulated 76ers vs. Heat 10,000 times and the results are in. We can tell you that the model is leaning over, and it’s also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Heat vs. 76ers? And which side of the spread hits almost 60 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its NBA picks.